Uphando lokukhawuleza inkawu (MPXV) ukuqhambuka kwavela ngo-Oktobha 2023 kwingingqi yaseKamituga yaseDemocratic Republic of the Congo (DRC) ibonise ukuba ukudibana ngokwesondo kwakuyindlela ephambili yosulelo losulelo. Oku kubalelwa kumnombo owahlukileyo weMPXV Clade Ib, owahlukileyo kulandelelwano lwangaphambili. clade Ndihlala e-DRC. Uhlobo lotshintsho beluphakamisa usulelo lwamva nje olusuka emntwini luye emntwini.
Amazwe amaninzi aseYurophu anike ingxelo ngokuqhubekayo ukwanda kwenani losulelo lwemonkeypox ukusukela ngoMeyi ka-2022. Amaqela amatyala anxulunyaniswa neziganeko ezinokuthi zenzeke zixelwe eBelgium, eSpain nase-United Kingdom. Amatyala angama-94,274 ewonke (ngomhla we-10 kuJanuwari ka-2024) axelwe kuyo yonke imimandla emithandathu ye-WHO.
Intsholongwane yemonkeypox (MPXV) yintsholongwane yeDNA enemisonto emibini esondelelene nengqakaqha. Yeyohlobo lwe-Orthopoxvirus kunye ne-vaccinia virus (VACV) kunye ne-variola virus (VARV) eyosulela abantu. Ngokutsho kwe-WHO yokuhlelwa kweZifo, kubangela "i-monkeypox (pox)". Iclade eyayisakuba yiCongo Basin ibizwa ngokuba yiClade one(I) kwaye iclade yangaphambili yaseNtshona Afrika ibizwa ngokuba yiClade two (II). UClade II ubandakanya amacandelwana amabini uClade IIa kunye noClade IIb.
Ukuqhambuka kwehlabathi kuka-2022 kubalelwa kwiintlobo ngeentlobo zeClade IIb.
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Iingxelo:
- Vakaniaki, EH et al 2024. Ukuqhambuka koLuntu okuZinzileyo kweMPXV entsha yeClade I Lineage kwiMpuma yeDemocratic Republic of the Congo. Ukuprintwa kwangaphambili kwi-medRxiv. Ithunyelwe nge-15 ku-Epreli 2024. DOI: https://doi.org/10.1101/2024.04.12.24305195
- Monzón, S., Varona, S., Negredo, A. et al. I-monkeypox virus ye-genomic accordion izicwangciso. UNat Commun 15, 3059 (2024). Ipapashwe: 18 April 2024. DOI: https://doi.org/10.1038/s41467-024-46949-7
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 outbreak that emerged in October 2023 in the Kamituga region of the Democratic Republic of the Congo (DRC) has revealed that sexual contact was a key mode of transmission of infection. This is attributed to a distinct MPXV Clade Ib lineage, divergent from previously sequenced Clade I strains in DRC. Type of mutations was suggestive of recent human-to-human transmission. ){kind=link}