Ngenxa yokuqhambuka okukhulu kunye nokukhula kwesifo semonkeypox (Mpox) eDemocratic Republic of the Congo (DRC) ngoku esele isasazekile ngaphandle kwelizwe kunye nokufumanisa uhlobo olutsha olwaqala ukuvela ngoSeptemba 2023 ngaphandle kwe-DRC, i-WHO imeme abavelisi bemveliso. izitofu zokugonya ze-mpox zokungenisa i-Expression of Interest for Emergency Use Listing (EUL) kubandakanywa idatha yokubonisa ukuba izitofu zokugonya zikhuselekile, ziyasebenza, zomgangatho oqinisekisiweyo kwaye zilungele abantu ekujoliswe kubo.
Inkqubo ye-EUL yinkqubo yogunyaziso losetyenziso olungxamisekileyo, ephuhliswe ngokukodwa ukukhawulezisa ukufumaneka kweemveliso zonyango ezingagunyaziswanga njengezitofu zokugonya ezifunekayo kwiimeko ezingxamisekileyo zempilo yoluntu. Ulwamkelo lwe-EUL luya kuphucula ukufumaneka kwesitofu sokugonya ngakumbi kwimimiselo enemiqobo yezibonelelo ezingekakhuphi eyazo imvume yolawulo lwesizwe. I-EUL ikwavumela amaqabane aquka i-Gavi kunye ne-UNICEF ukuba athenge amayeza okugonya ukuze asasazwe.
Intsholongwane yemonkeypox (MPXV) yintsholongwane ye-DNA ephindwe kabini yohlobo lwe-Orthopoxvirus kunye ne-vaccinia virus (VACV) kunye ne-variola virus (VARV). Ihlobene ngokusondeleyo nengqakaqha, eyona ntsholongwane yabulala abantu abaninzi embalini ebangele ukuphanziswa kwabantu ngokungenakuthelekiswa nanto kwiinkulungwane ezidluleyo. Ngokupheliswa okupheleleyo kunye nokupheliswa kwenkqubo yokugonya ingqakaqha (eyayibonelele ngokhuseleko olunqamlezileyo kwintsholongwane yemonkeypox), inani labemi langoku linamanqanaba ancitshisiweyo okugonyeka kweli qela leentsholongwane. Oku kucacisa ngokufanelekileyo ukunyuka kunye nokusasazeka kwentsholongwane yemonkeypox kwiindawo ezihlala kuyo eAfrika.
I-Mpox sisifo esibangelwa yintsholongwane ye-monkeypox. I-Mpox inokosulela ebantwini ngokudibana ngokwasemzimbeni nabantu abosulelekileyo, okanye ngezinto ezisulelekileyo, okanye nezilwanyana ezosulelekileyo.
Ugonyo lwe-Mpox olusetyenziswayo ngoku:
Kubantu abadala abanempilo, ukungaphindi (MVA-BN), ukuphindaphinda okuncinci (LC 16) okanye ukuphindaphinda izitofu ezisekelwe kwi-vaccinia (ACAM2000) zifanelekile.
I-MVA-BN sisitofu sokugonya se-mpox sesizukulwana se-3 esilawulwa njengedosi ezimbini ze-subcutaneous naliti enikezelwa ubuncinane kwiiveki ezi-4 ngaphandle. Zombini i-1 kunye ne-2 iidosi ze-MVA-BN zisebenza kakhulu ekuthinteleni i-mpox.
I-LC16 kunye ne-ACAM2000 sisitofu sokugonya se-mpox sedosi enye.
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Iingxelo:
- Ukukhutshwa kwe-WHO Press - WHO imema abavelisi bokugonya i-mpox ukuba bangenise iidosi zovavanyo olungxamisekileyo. Ipapashwe nge-09 Agasti 2024. Ifumaneka e https://www.who.int/news/item/09-08-2024-who-invites-mpox-vaccine-manufacturers-to-submit-dossiers-for-emergency-evaluations
- I-WHO. Ugonyo kunye nogonyo lwemonkeypox: Isikhokelo sethutyana, 16 Novemba 2022. Ifumaneka kwa https://iris.who.int/bitstream/handle/10665/364527/WHO-MPX-Immunization-2022.3-eng.pdf
- I-Pischel L., et al 2024. Ukusebenza kwesitofu sokugonya se-3 yesizukulwana sempox sokugonya ngokuchasene ne-mpox kunye nobunzima besifo: Uphononongo olucwangcisiweyo kunye nohlalutyo lwemeta. Isitofu sokugonya. Ifumaneka kwi-intanethi nge-21 Juni 2024. DOI: https://doi.org/10.1016/j.vaccine.2024.06.021
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Amanqaku afanelekileyo
Uxinzelelo lweNkawu lweNkawu (MPXV) Lusasazeke ngokuNxibelelana ngokwesondo (20 Epreli 2024)
Intsholongwane yemonkeypox (MPXV) ezahlukeneyo ezinikwe amagama amatsha (I-12 Agasti 2022)
Ngaba iMonkeypox iya kuhamba ngendlela yeCorona? (23 Juni 2022)
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