Kutheni i-Omicron kufuneka ithathwe ngokungathí sina

Ubungqina ukuza kuthi ga ngoku bucebisa ukuba ukwahluka kwe-Omicron ye-SARS-CoV-2 inezinga eliphezulu losulelo kodwa ngethamsanqa iphantsi kobugwenxa kwaye ayiqhelekanga ukukhokelela kwiimpawu ezinzima ze-COVID-19 okanye ukufa. Kodwa izitofu zokugonya ezikhoyo zibonakala zingasebenzi kakuhle njengoko inani losulelo oluyimpumelelo luxeliwe. Xa kukho inani elikhulu leemeko ze-Omicron ezineempawu ezifuna isigulane ukhathalelo lwesibhedlele, kukho ithuba lokuba inkqubo yezempilo yonganyelwe. Nangona kunjalo, isoyikiso esibi kakhulu esivezwa kukwahluka kwe-Omicron kukuba nokwenzeka kokuvela kwalo naluphi na uhlobo olutsha olunobugwenxa obuphezulu ngenxa yeepaseji ezilandelelanayo (ukudluliselwa) kweentsholongwane phakathi kwabantu. Kuyabonakala ukuba, le yindlela eyahluka ngayo i-delta enobuqhophololo ethe yavela kwiiyantlukwano zangaphambili ngeqondo eliphezulu kakhulu losulelo phakathi kwabantu. Ke ngoko, ukunqanda ukuhamba kwentsholongwane phakathi kwabantu okt, ukophula ikhonkco losulelo ngokusebenzisa iimaski zobuso, ukuhamba kude ngokwasemzimbeni kunye neendibano ezityhafisayo ngundoqo.   

Kukho ingxelo ye Micron kunye neempawu ezibandayo zithatha ngokukhawuleza eLondon.  

Ngokophononongo lwe-ZOE COVID, lilonke ngoku kukho ama-87,131 eemeko ezintsha zemihla ngemihla ezineempawu ze-COVID e-UK ngokomndilili. Ukunyuka nge-4% ukusuka kuma-83,658 amatyala amatsha emihla ngemihla kwiveki ephelileyo. Ukubaleka impumlo, intloko ebuhlungu, ukudinwa (nokuba kuphakathi okanye kuqatha), ukuthimla kunye nomqala obuhlungu zezona mpawu zintlanu ziphezulu zixeliweyo. Iimpawu ezinje ngokubanda zibonakala ziluphawu oluphambili lweOmicron. Kubemi abagonywe ngokupheleleyo, ngoku kukho ama-27,000 eemeko ezintsha zemihla ngemihla ezineempawu e-UK. Ukunyuka nge-6% ukusuka kwi-25,411 yamatyala amatsha emihla ngemihla kwiveki ephelileyo¹.  

Ngokujonga uguquko olubanzi, bekulindeleke ukuba ukwahluka kwe-Omicron kuphephe iimpendulo zomzimba ukuya kuthi ga kwinqanaba elithile. Kuphononongo lwabantu abafumene iidosi ezimbini zesiqhelo kunye nedosi ye-booster yezitofu zokugonya ze-mRNA, zonke izigulana zafunyaniswa zineempawu ezithambileyo ukuya kweziphakathi ze-COVID-19 zinika umbono wokuba iidosi ezintathu zogonyo lwe-mRNA zinokungonelanga ukunqanda usulelo kunye neempawu. isifo². Ngokukwanjalo, kolunye uphononongo olubandakanya ulawulo lwedosi ye-booster yesitofu sokugonya se-COVID-19 se-BBIBP-CorV, abaphandi babone ukuphindaphinda okubalulekileyo ekuthinteleni ukuphendula komzimba ngokuchasene ne-SARS-CoV-2 nangona kunjalo ukwahluka kwe-Omicron kubonise ukubaleka okubanzi kodwa okungaphelelanga kwe-booster ephakanyisiweyo. ukungathathi hlangothi³. 

Ngaphandle kweemeko zogonyo lwempumelelo, iimeko ze-Omicron zihlala zinganxulunyaniswa neempawu ezinzima ze-COVID-19. Kunye kuphela ukufa okunxulumene ne-Omicron okuye kwaxelwa e-UK ukuza kuthi ga ngoku. Nangona kunjalo, xa kukho inani elikhulu leemeko ze-Omicron ezineempawu ezifuna ukhathalelo lwesibhedlele kwisigulane, kukho umngcipheko wokuba inkqubo yezempilo yonganyelwe. Kodwa isisongelo esikhulu sinxulunyaniswa nemeko yalo eyosulela kakhulu.   

Kusekwe ukuba iOmicron okwahlukileyo ingaphezulu ngokuphindwe kane ukosuleleka okanye ukosulela kunokwahluka kwedelta. Kwisithuba esingaphantsi kwenyanga ukusukela oko kwaxelwa okokuqala i-Omicron eMzantsi Afrika, isasazeke kwihlabathi jikelele. Ekuqaleni, amatyala afunyenweyo ayenxulumene nokuhamba, kodwa ngoku uninzi lwamazwe achaphazelekayo abona inqanaba eliphezulu losulelo loluntu. Izinga eliphezulu losulelo ngumba oxhalabisayo kuba uninzi lweepaseji ezilandelelanayo zentsholongwane phakathi kwabantu abosulelekileyo zinokuba negalelo ekuveleni kolunye uhlobo oluyingozi ngakumbi kwixesha elizayo.  

IiCoronaviruses azinamsebenzi wokuvavanya i-nuclease yeepolymerase zabo yiyo loo nto iimpazamo zokuphindaphinda zihlala zingalungiswa ezithi ziqokelele kwaye zibe negalelo kutshintsho. Usulelo oluninzi luthetha iimpazamo eziphindaphindayo kungoko iinguqu ezininzi ziqokelelana kwijenome yentsholongwane ekhokelela ekuveleni kwezinto ezintsha ezahlukeneyo. Ii-coronavirus zabantu zisakha iinguqulelo ukwenza izinto ezintsha kwimbali yamva nje⁴. Kuyabonakala ukuba, le yindlela okwahluka kwe-delta eyingozi kakhulu evele ngayo kwiiyantlukwano zangaphambili ngenqanaba eliphezulu kakhulu losulelo phakathi kwabantu. 

Ngemibhiyozo yeKrisimesi kunye noNyaka oMtsha isendleleni, umngcipheko wokuvela kwayo nayiphi na into entsha enobugwenxa obuphezulu ngenxa yeendinyana ezininzi ze-serial (ukuhanjiswa) kweentsholongwane phakathi kwabantu kuye kwanyanzela amazwe amaninzi anjengeNetherland, UK kunye neFransi ukunyanzelisa ukutshixa njengezithintelo. 

Ukunciphisa usulelo kunye nokwaphulwa kwe Ukuhanjiswa chain isitshixo. Izenzo ezilungileyo zakudala zokusetyenziswa kweemaski zobuso, ukuhamba kude ngokwasemzimbeni kunye nokuphepha iindibano ezinkulu kufuneka zibe luncedo kakhulu.  

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Iingxelo:   

1. Uphononongo lwe-ZOE COVID, ngo-2021. Ukukhutshwa kweDatha -I-Omicron kunye neempawu ezibandayo ezithatha ngokukhawuleza eLondon. Ipapashwe nge-16 kaDisemba 2021. Iyafumaneka kwi-intanethi https://covid.joinzoe.com/post/omicron-and-cold-like-symptoms-rapidly-taking-over-in-london 
2. Kuhlmann C., okqhubekayo Ngo-2021. Usulelo oluQhelekileyo nge-SARS-CoV-2 Omicron Variant Ngaphandle kweDose yeBooster ye-mRNA Vaccine. Ipapashwe: 9 December 2021. DOI: http://dx.doi.org/10.2139/ssrn.3981711 
3. Yu X., okqhubekayo 2021. IPseudotyped SARS-CoV-2 Omicron eyahlukileyo ibonisa ukubaleka okubalulekileyo kokungathathi hlangothi okubangelwa idosi yesithathu yokukhuthaza ukugonywa. Shicilela kwangaphambili medRxiv. Iposwe nge-18 kaDisemba 2021. DOI: https://doi.org/10.1101/2021.12.17.21267961 
4. Prasad U., 2021. Iintlobo ezahlukeneyo zeCoronavirus: Oko Sikwaziyo ukuza kuthi ga ngoku. Inzululwazi yaseYurophu. Ithunyelwe nge-12 kaJulayi 2021. Iyafumaneka kwi-intanethi https://www.scientificeuropean.co.uk/covid-19/variants-of-coronavirus-what-we-know-so-far/ 

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