Kubekho ukonyuka okukhawulezayo kokwahluka kwe-delta ye-SARS CoV-2 eFransi ngoJuni ka-2021 ngokusekwe kuhlalutyo lweesampulu ezilungileyo ezingama-5061.1. Iiveki ezimbalwa ezizayo zibaluleke kakhulu ngokubhekiselele ekuveleni kwamaza esithathu ngenxa yokudluliselwa okuphezulu kwe-delta eyahlukileyo kunye nefuthe eliya kuba nalo kwinkqubo yokhathalelo lwempilo yoluntu kunye neyobucala. Ukufa kunye nokugula okuya kudibaniswa namaza esithathu kuya kuxhomekeka ekusebenzeni kwe-AstraZeneca ChAdOx1. lokugonya, kwi-delta eyahlukileyo, enikezelwe kubemi.
Uhlalutyo lwabemi base-UK olufumene idosi yokuqala neyesibini ye I-ChAdOx1 isitofu sokugonya sityhila ukuba emva kwethamo lokuqala, isitofu sokugonya besingasebenzi kakuhle (33.5% ngokuchasene ne-B.1.617.2 [umohluko wedelta] xa kuthelekiswa nama-51.1% ngokuchasene nokwahluka kwe-B.1.1.7)2. Ukongeza, emva kwedosi yesibini kwakhona, isitofu sokugonya sasingasebenzi kakuhle (59.8% ngokuchasene ne-B.1.617.2 [ukwahlukana kwe-delta] xa kuthelekiswa ne-66.1% ngokuchasene nokwahluka kwe-B.1.1.7)2.
Kutheni sibona amaza ahlukeneyo Covid-19 kumazwe awahlukahlukeneyo ngamaxesha ahlukeneyo? Impendulo isenokuthi ukhuseleko lomhlambi alukafikeleli kwaye “ukuvalelwa" isusiwe yakhokelela kumaza alandelayo e-COVID-19. “Ukutshixa” enyanisweni kuthintela usulelo lwentsholongwane kwaye ngaloo ndlela kuthintela ukuphindaphindeka kwentsholongwane kunye notshintsho. Nangona kunjalo, umceli mngeni ojongene nawo yeyokuba ixesha ngalinye iliza lisiza, intsholongwane ifumana ithuba lokuziguqula nto leyo enokuthi ibangele ukosuleleka ngakumbi (uhlobo lwentsholongwane olunosulelo olukhulu olukhokelela ekubambeleleni ekusindeni kwethiyori inamandla), ngaloo ndlela iyala isiphumo se ukungazinzi komzimba ifikeleleke ngokuchasene nokwahluka kwangaphambili kwentsholongwane. Kutshanje, kwavela uhlobo olutsha olubizwa ngokuba yi-delta plus edibanisa umahluko we-delta kunye noguqulo lwe-K417N (eqale yafunyanwa kumohluko weBeta owavela eMzantsi Afrika). Le delta plus eyahlukileyo ayinyangeki kunyango lwe-antibody. Konke oku kubangela umngeni onzima malunga nokufikelela kukhuselo lomhlambi.
Ukungafikeleki komzimba3 kusengafikelelwa ukuba izitofu zokugonya ezilawulwayo zibonelela ngokhuseleko olubalulekileyo ubuncinane olungaphezulu kwe-90% njengoko ibango lezitofu zokugonya ze-mRNA ze-Pfizer kunye neModerna (93.4% kunye needosi ezi-2 ze-Pfizer ngokuchasene nokwahluka kwe-B.1.1.7 kunye ne-87.9% ngokuchaseneyo i-B.1.617.2 [ukwahluka kwedelta]). Nangona kunjalo, ezi zitofu zisetyenziswa ikakhulu e-USA nase-UK, ngelixa amanye amazwe exhomekeke ikakhulu kwisitofu sokugonya se-ChAdOx1 (AstraZeneca), isitofu sokugonya saseRussia iSputnik V kunye nesitofu sokugonya sase-Indian Covaxin. Ezi zitofu zinokunikezela okanye zinganikezeli ugonyo olusebenzayo ngokuchasene nokwahluka okwenziwa ngokutsha. Ukungabikho kogonyo olusebenzayo kunye nenyaniso yokuba iintlobo ezintsha ezisuleleka kakhulu ziye ziveliswa phantse ngalo lonke ixesha intsholongwane iphindaphinda ikhokelela kuguquko, kunokuthatha iinyanga ezininzi ukufikelela kukhuseleko olufanelekileyo lomhlambi kwaye amaza alandelayo e-COVID-19 aya kuqhubeka de umhlambi osebenzayo. ukugonyeka kufezekiswa.
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Ucaphulo
- Alizon S., Haim-Boukobza S., et al 2021. Ukusasazeka ngokukhawuleza kwe-SARS-CoV-2 δ ukwahluka kwindawo yaseParis (France) ngoJuni 2021. Ithunyelwe nge-20 kaJuni ngo-2021 kwi-Preprint medRxiv. DOI: https://doi.org/10.1101/2021.06.16.21259052
- UBernal JL, u-Andrews N, uGower C et al. Ukusebenza kogonyo lwe-COVID-19 ngokuchasene nokwahluka kwe-B.1.617.2. Ithunyelwe nge-24 kuMeyi, 2021. DOI: https://doi.org/10.1101/2021.05.22.21257658
- Soni R 2021. I-COVID-19: uVavanyo lokugonywa koMhlambi kunye noKhuseleko lwesitofu. Iyafumaneka kwi-intanethi https://www.scientificeuropean.co.uk/covid-19/covid-19-an-evaluation-of-herd-immunity-and-vaccine-protection/
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