Uphononongo lwe-ISARIC olusandul 'ukugqitywa kuhlaziyo lwabaguli abayi-16749 abanesifo esiqatha se-COVID-19 kwizibhedlele ezili-166 lubonise ukuba abo bane-co-morbidity babesemngciphekweni omkhulu ngelixa abo bangenayo i-comorbidity ibalulekileyo bephuma bephila becebisa abantu abangenazo iimeko zokugula. angavunyelwa ukuba abuyele emsebenzini ngononophelo.
Uphononongo olugqitywe kutshanje e-UK ngokubanzi, olubizwa ngokuba yi-International Severe Acute Respiratory Infection Consortium. (ISARIC) isifundo inika ukukhanya kwizinto ezimisela ukusweleka kunye nokugula kwizigulana ezosulelwe sisifo se-COVID-19. Uphononongo lwenziwe kwizibhedlele ezili-166 e-UK yimanyano yabaphandi kwizigulana ezili-16749 ezosulelwe yile ntsholongwane. Covid-19. Idatha yaqokelelwa kusetyenziswa uluhlu lwemibuzo oluvunywe kwangaphambili olwamkelwa yi-WHO.
Malunga ne-47% yabaguli ababhalise kuphononongo babengenayo enye imeko yokugula ngaphandle kwe-COVID-19. Abanye babenesifo sentliziyo, isifo sombefu, isifo seswekile kunye nesifo semiphunga esinganyangekiyo. Ubudala obuphakathi bezigulane kuphononongo yiminyaka eyi-72 kunye nobude bexesha eliphakathi kweempawu ngaphambi kokungeniswa kweentsuku ze-4.
Iziphumo zophononongo bezinomdla kakhulu. Phantse i-49% yezigulana ezili-16749 zakhutshwa ziphila, ezingama-33% zasweleka ngelixa ezinye iipesenti ezili-17 bezidinga ukhathalelo olumandla kunye nokuxhomekeka okuphezulu kungenelelo lwezonyango. Oku kwenza malunga nama-2800 ezigulane eziye zafumana unyango kwiiyunithi zabagula kakhulu. Kwizigulana ezifumana ukhathalelo olunzulu kunye nongenelelo olunzulu lwezonyango, i-31% yakhululwa esaphila, i-45% yasweleka kwaye i-24% iqhubekile nokufumana ukhathalelo de kube ngumhla wokunika ingxelo. Intelekelelo enika umdla enokuqondwa apha kukuba ~isiqingatha sezigulane ezili-16749 zaye zakhululwa ziphila ngelixa inani elifanayo lingenaso esinye isifo sokugula xa samkelwe. Oku kucebisa ukuba nabantu abadala abaneminyaka emalunga nama-72 ubudala bayakwazi ukuchacha kwisifo se-COVID-19, ngaphandle kokuba abanayo nayiphi na imeko ekhoyo ngaphambili.
Emva kokudibanisa zonke iziphumo, iguqulela kwi-54% yezinga lokusinda kwinani elipheleleyo lezigulane ezibhaliswe kuphononongo, i-40% yokufa kunye ne-6% iqhubekile ifumana ukhathalelo olunzulu. Kukho ukonyuka kwe-7% kwizinga lokusinda ukuba izigulane zifumene unyango olunzulu kunye nokwanda okufanayo kokufa nangona zinikwe ukhathalelo olunzulu.
Ukushwankathela, izinga lokusweleka liphezulu kakhulu kwizigulana ze-COVID-19 (~ 90% yezigulana ezazinemeko enxulumene ne-co-morbid kwaye zifuna ukhathalelo olunzulu) esele inemeko ebisele ikho ekhankanywe kwisitanza sesi-2 ngasentla. Olunye uphononongo olubalulekileyo olufunyenwe kolu phononongo yayikukuba abantu abangamadoda batyebe kakhulu batyekele kakhulu ekubeni ne-COVID-19 kunye nokufa kwabantu ukongeza kwiimeko esele zikhankanyiwe ezibangela ukusweleka.
Ukuqikelelwa kolu phando kuya kunceda ekuchazeni nasekuphunyezweni kwamanyathelo acwangcisiweyo ngokumalunga noku Ukuncitshiswa kwentlalo ukuqhubela phambili ukuze kukhuselwe abantu abadala kunye nolutsha ngakumbi abo banemeko yesigulo esele inxulumene njengoko kuchaziwe, kunye nokuvumela abanye abantu ukuba baphuhlise ukukhuseleka komhlambi, ngaloo ndlela kugcinwe ixabiso elikhulu leendleko kunye nokunciphisa ilahleko kuqoqosho lwehlabathi esijongene nalo. okwangoku.
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Iingxelo:
Docherty, Annemarie B., Harrison, Ewen M., et al 2020. Iimpawu ze-16,749 lezigulana ezilaliswe esibhedlele zase-UK ezine-COVID-19 usebenzisa i-ISARIC WHO Clinical Characterization Protocol. Ushicilelo lwangaphambili luPoswe kwi-medRxiv nge-28 ka-Epreli 2020.
DOI: https://doi.org/10.1101/2020.04.23.20076042
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Amagqabantshintshi zivaliwe.